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Selected Books by Edmund Blair Bolles

  • Galileo's Commandment: 2500 Years of Great Science Writing
  • The Ice Finders: How a Poet, a Professor, and a Politician Discovered the Ice Age
  • Einstein Defiant: Genius vs Genius in the Quantum Revolution

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Carl

One area that I feel impeeds the research of neurological music research is the inability to look at models of genetic manipulation to see the effect. In other areas of research for bacteriology or alzheimers researchers can manipulate gene expression in model organisms to document the effect. This scientific approach is useless in our area for two reasons 1) ethics 2) the view of music to be a human specific behavior.

If FOXP2 does indeed code for proteins which are reasponsible for receptor / transmittor action in regions of the brain associated with language, the next logical step is to model our experiments for FOXP2.
This can be done in two ways - take organisms known to communicate such as lower primates / elephants / dolphins - what have you and knock out expression of the FOX2 gene. If communication is altered, we are on a good step. The other alternative may be to design agonists and antagonists for the receptor for use in clinical research.
Imagine the possibilities if a drug stimulating these receptors can enhance musical ability to make us all Mozarts!

Barry Gibbon

Has anyone suggested genetically manipulating chimps with foxp2? Given their genetic similarity with human, we could winnow down the full range of effects of the FOXP2. Has this been tried? Is it ethical? (Shades of Planet of the Apes, yes?)

John

I think there needs to be more research done about FoxP2 to discover more information about this.

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